Vitamin D deficiency increases UTI riskAssociation of Posttransplant Circulating 25-Hydroxyvitamin D and Late-Onset Infections Among Kidney Transplant Recipients: The Wisconsin Allograft Recipient Database (WisARD).
Highly relevant infection prevention study
We explored the link between vitamin D levels and late-onset urinary tract infections (UTIs) among kidney transplant recipients. Our study analyzed data from 2,207 individuals who had measurements of their vitamin D levels after transplantation.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
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Vitamin D's role in UTIsSerum Vitamin D and Zinc Levels in Children with Urinary Tract Infection without Confounding Factors: A Case-Control Study.
Highly relevant to pediatric UTIs
We explored the relationship between vitamin D levels and urinary tract infections (UTIs) in children. In our study, we assessed the serum vitamin D and zinc levels among two groups: 40 healthy children and 40 children suffering from UTIs, ensuring that no other health factors influenced the results.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
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Vitamin D linked to UTIsThe Association between Serum Vitamin D Levels and Urinary Tract Infection Risk in Children: A Systematic Review and Meta-Analysis.
Direct study on children
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
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We set out to explore the link between vitamin D deficiency and urinary tract infections (UTIs) in children. Our research included a well-defined case-control study with children aged one to five years. We compared 82 children experiencing their first febrile UTI to 82 healthy peers.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
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We conducted a study to investigate the relationship between vitamin D levels and urinary tract infections (UTIs) in children. This case-control research involved 80 children, aged between 1 and 12 years, who had been diagnosed with UTIs. For every child in the UTI group, we matched a control child of the same age and sex who did not have a UTI.
We measured the serum vitamin D levels using a method called ELISA. The results were telling. Our findings revealed that children with UTIs had significantly lower levels of vitamin D compared to their healthy peers. In fact, the odds of having a UTI were more than three times greater for those with low vitamin D levels.
Interestingly, we observed that this connection was particularly pronounced in female children. They showed an even higher risk of UTI when their vitamin D levels were low. As for male children, we didn't find a significant difference in vitamin D levels between those with UTIs and those without.
Our conclusions highlight a vital relationship between vitamin D deficiency and the prevalence of UTIs in children. Not only does vitamin D deficiency appear to increase the risk of UTIs, but female gender also seems to be a prominent risk factor.
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